Log into Quickbooks as THE "Admin". Then switch it to single-user mode.
In QuoteWerks, click on the QuickBooks icon, then click on the Setup Button in the bottom left.
QuickBooks should start flashing, click over to it and you should see the screen to allow QuoteWerks access to QuickBooks
Click Continue. QuoteWerks should be able to communicate with QuickBooks now when the company file is open.
At this point you can set up the link between QuoteWerks and QuickBooks. Information on this can be found at http://www.quotewerks.com/helpfile/qwhelp.htm?settinguptheinteractivequickbookslink.htm