Do you have the same if you change the QuoteWerks Appearance to "System"?
Tools > My Preferences > Appearance
Just updated to build 5.10, and the issue occurred immediately (and had to X-out and restart).
Confirmed 'Appearance' is already set to 'System'.
Do you have the same issue if the QuoteWerks screen is not maximised?
Yes, same issue whether or not maximized.
We have found for certain Windows 10 installs, you actually have to turn ON one of the appearance skins for the menus to stay consistently available.
I don't know which specific builds of Windows, it has seemed to be random, but this will usually make the menus available again.
This appears to have fixed the issue (setting an appearance skin). Thank you.